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1

Aprt/Opn double knockout mice: Osteopontin is a modifier of kidney stone disease severity

Vernon, Hilary J., Osborne, Christine, Tzortzaki, Eleni G., Yang, Min, Chen, Jianmen, Rittling, Susan R., Denhardt, David T., Buyske, Steven, Bledsoe, Sharon B., Evan, Andrew P., Fairbanks, Lynette, S

Journal:

Kidney International

Year:

2005

Language:

english

File:

PDF, 353 KB

english, 2005

2

OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application

Chooryung J. Chung, Kunimichi Soma, Susan R. Rittling, David T. Denhardt, Tadayoshi Hayata, Kazuhisa Nakashima, Yoichi Ezura, Masaki Noda

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 348 KB

english, 2008

3

R OLE OF O STEOPONTIN IN C ELLULAR S IGNALING AND T OXICANT I NJURY1

Denhardt, David T, Giachelli, Cecilia M, Rittling, Susan R

Journal:

Annual Review of Pharmacology

Year:

2001

Language:

english

File:

PDF, 324 KB

english, 2001

4

Instability of endogenous MRP/proliferin transcripts in the nucleus of mouse embryo fibroblasts contrasts with their stability when produced during transient transfections

Uriel M. Malyankar, Susan R. Rittling, David T. Denhardt

Journal:

Journal of Cellular Biochemistry

Year:

1996

Language:

english

File:

PDF, 1.26 MB

english, 1996

5

Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice

Yuichiro Matsui, Norimasa Iwasaki, Shigeyuki Kon, Daisuke Takahashi, Junko Morimoto, Yutaka Matsui, David T. Denhardt, Susan Rittling, Akio Minami, Toshimitsu Uede

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 670 KB

english, 2009

6

Osteopontin deficiency impairs wear debris–induced osteolysis via regulation of cytokine secretion from murine macrophages

Sadanori Shimizu, Naoki Okuda, Norihiko Kato, Susan R. Rittling, Atsushi Okawa, Kenichi Shinomiya, Takeshi Muneta, David T. Denhardt, Masaki Noda, Kunikazu Tsuji, Yoshinori Asou

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 289 KB

english, 2010

7

Regulatory role of DC-derived osteopontin in systemic allergen sensitization

Masatsugu Kurokawa, Satoshi Konno, Ayumu Takahashi, Beverly Plunkett, Susan R. Rittling, Yutaka Matsui, Shigeyuki Kon, Junko Morimoto, Toshimitsu Uede, Satoshi Matsukura, Fumio Kokubu, Mitsuru Adachi,

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 289 KB

english, 2009

8

Serum osteopontin, an enhancer of tumor metastasis to bone, promotes B16 melanoma cell migration

Chikako Hayashi, Susan Rittling, Tadayoshi Hayata, Teruo Amagasa, David Denhardt, Yoichi Ezura, Kazuhisa Nakashima, Masaki Noda

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 158 KB

english, 2007

9

Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to post-translational modifications

Christian C. Kazanecki, Aaron J. Kowalski, Tony Ding, Susan R. Rittling, David T. Denhardt

Journal:

Journal of Cellular Biochemistry

Year:

2007

Language:

english

File:

PDF, 340 KB

english, 2007

10

Transforming growth factor-β1 regulation of ATF-3 and identification of ATF-3 target genes in breast cancer cells

Sukyee Kwok, Susan R. Rittling, Nicola C. Partridge, Chellakkan S. Benson, Mayuranathan Thiyagaraj, Narasimhan Srinivasan, Nagarajan Selvamurugan

Journal:

Journal of Cellular Biochemistry

Year:

2009

Language:

english

File:

PDF, 218 KB

english, 2009

11

Amino acid pools in cultured muscle cells

Robert B. Low, William S. Stirewalt, Susan R. Rittling, Robert C. Woodworth

Journal:

Journal of Cellular Biochemistry

Year:

1984

Language:

english

File:

PDF, 473 KB

english, 1984

12

Osteopontin modulates CD44-dependent chemotaxis of peritoneal macrophages through G-protein-coupled receptors: Evidence of a role for an intracellular form of osteopontin

Baoqian Zhu, Keiko Suzuki, Harvey A. Goldberg, Susan R. Rittling, David T. Denhardt, Christopher A.G. McCulloch, Jaro Sodek

Journal:

Journal of Cellular Physiology

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

13

Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-α expression and non-programmed cell death

Andre Paes Batista da Silva, Aaron Pollett, Susan R. Rittling, David T. Denhardt, Jaro Sodek, Ron Zohar

Journal:

Journal of Cellular Physiology

Year:

2006

Language:

english

File:

PDF, 552 KB

english, 2006

14

Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene

Noiri, Eisei, Dickman, Kate, Miller, Frederick, Romanov, Galina, Romanov, Victor I, Shaw, Robert, Chambers, Ann F, Rittling, Susan R, Denhardt, David T, Goligorsky, Michael S

Journal:

Kidney International

Year:

1999

Language:

english

File:

PDF, 507 KB

english, 1999

15

A Mouse Model of Breast Cancer Metastasis to the Choroid of the Eye

Misty Kuhn, Sarah Shah, Tajneen Natasha, Susan R. Rittling

Journal:

Clinical and Experimental Metastasis

Year:

2005

Language:

english

File:

PDF, 231 KB

english, 2005

16

Protective role of osteopontin in endodontic infection

Susan R. Rittling, Craig Zetterberg, Kader Yagiz, Stephen Skinner, Noriyuki Suzuki, Akira Fujimura, Hajime Sasaki

Journal:

Year:

2010

Language:

english

File:

PDF, 383 KB

english, 2010

17

Apatite plaque particles in inner medulla of kidneys of calcium oxalate stone formers: Osteopontin localization

EVAN, ANDREW P, COE, FREDRIC L, RITTLING, SUSAN R, BLEDSOE, SHARON M, SHAO, YOUZHI, LINGEMAN, JAMES E, WORCESTER, ELAINE M

Journal:

Kidney International

Year:

2005

Language:

english

File:

PDF, 754 KB

english, 2005

18

Characterization of osteopontin expression and function after status epilepticus

Karin Borges, Marla Gearing, Susan Rittling, Esben S. Sorensen, Robert Kotloski, David T. Denhardt, Raymond Dingledine

Journal:

Year:

2008

Language:

english

File:

PDF, 898 KB

english, 2008

19

Mice Lacking Osteopontin Show Normal Development and Bone Structure but Display Altered Osteoclast Formation In Vitro

Susan R. Rittling, Hiroko N. Matsumoto, Marc D. Mckee, Antonio Nanci, Xiao-Rong An, Kristine E. Novick, Aaron J. Kowalski, Masaki Noda, David T. Denhardt

Journal:

Journal of Bone and Mineral Research

Year:

1998

Language:

english

File:

PDF, 444 KB

english, 1998

20

Osteopontin Deficiency Reduces Experimental Tumor Cell Metastasis to Bone and Soft Tissues

Hiroyuki Nemoto, Susan R. Rittling, Hiroyuki Yoshitake, Koichi Furuya, Teruo Amagasa, Kunikazu Tsuji, Akira Nifuji, David T. Denhardt, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2001

Language:

english

File:

PDF, 1.28 MB

english, 2001

21

Resistance to Unloading-Induced Three-Dimensional Bone Loss in Osteopontin-Deficient Mice

Muneaki Ishijima, Kunikazu Tsuji, Susan R. Rittling, Teruhito Yamashita, Hisashi Kurosawa, David T. Denhardt, Akira Nifuji, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2002

Language:

english

File:

PDF, 4.73 MB

english, 2002

22

Osteopontin-Deficiency Suppresses Growth of B16 Melanoma Cells Implanted in Bone and Osteoclastogenesis in Co-Cultures

Yoshio Ohyama, Hiroyuki Nemoto, Susan Rittling, Kunikazu Tsuji, Teruo Amagasa, David T Denhardt, Akira Nifuji, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2004

Language:

english

File:

PDF, 903 KB

english, 2004

23

Osteopontin Expression in Osteoblasts and Osteocytes During Bone Formation Under Mechanical Stress in the Calvarial Suture In Vivo

Mikihiko Morinobu, Muneaki Ishijima, Susan R Rittling, Kunikazu Tsuji, Haruyasu Yamamoto, Akira Nifuji, David T Denhardt, Masaki Noda

Journal:

Journal of Bone and Mineral Research

Year:

2003

Language:

english

File:

PDF, 3.37 MB

english, 2003

24

Mammary tumor development in MMTV-c-myc/MMTV-v-Ha-ras transgenic mice is unaffected by osteopontin deficiency

Fei Feng, Susan R. Rittling

Journal:

Breast Cancer Research and Treatment

Year:

2000

Language:

english

File:

PDF, 127 KB

english, 2000

25

Transcriptional regulation of osteopontin and the metastatic phenotype: Evidence for a Ras-activated enhancer in the human OPN promoter

David T. Denhardt, Devra Mistretta, Ann F. Chambers, Shuba Krishna, Joseph F. Porter, Srilatha Raghuram, Susan R. Rittling

Journal:

Clinical and Experimental Metastasis

Year:

2003

Language:

english

File:

PDF, 160 KB

english, 2003

26

Novel murine mammary epithelial cell lines that form osteolytic bone metastases: Effect of strain background on tumor homing

Yanping Chen, Susan R. Rittling

Journal:

Clinical and Experimental Metastasis

Year:

2003

Language:

english

File:

PDF, 338 KB

english, 2003

27

Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice

Brenda Bourassa, Sara Monaghan, Susan R. Rittling

Journal:

Cellular Immunology

Year:

2004

Language:

english

File:

PDF, 315 KB

english, 2004

28

Osteopontin is associated with nuclear factor κB gene expression during tail-suspension-induced bone loss

Muneaki Ishijima, Yoichi Ezura, Kunikazu Tsuji, Susan R. Rittling, Hisashi Kurosawa, David T. Denhardt, Mitsuru Emi, Akira Nifuji, Masaki Noda

Journal:

Experimental Cell Research

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

29

Promoter-independent regulation of vimentin expression in mammary epithelial cells by val12 ras and TGFβ

Bradley Yates, Craig Zetterberg, Vaishali Rajeev, Michael Reiss, Susan R. Rittling

Journal:

Experimental Cell Research

Year:

2007

Language:

english

File:

PDF, 1.54 MB

english, 2007

30

Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation

Kader Yagiz, Susan R Rittling

Journal:

Experimental Cell Research

Year:

2009

Language:

english

File:

PDF, 2.75 MB

english, 2009

31

Detection of Mouse Osteopontin by Western Blotting

Susan R. Rittling, Fei Feng

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 379 KB

english, 1998

32

Cell Cycle-Dependent Regulation of Ca2+ in Young and Senescent WI-38 Cells

Katherine M. Brooks-Frederich, Felicia L. Cianciarulo, Susan R. Rittling, Vincent J. Cristofalo

Journal:

Experimental Cell Research

Year:

1993

File:

PDF, 203 KB

1993

33

Clonal Nature of Spontaneously Immortalized 3T3 Cells

Susan R. Rittling

Journal:

Experimental Cell Research

Year:

1996

Language:

english

File:

PDF, 215 KB

english, 1996

34

Ferritin synthesis in rat L-6 cells: Response to iron challenge

Susan R. Rittling, Robert C. Woodworth

Journal:

Archives of Biochemistry and Biophysics

Year:

1983

Language:

english

File:

PDF, 1.37 MB

english, 1983

35

Bone sialoprotein, but not osteopontin, deficiency impairs the mineralization of regenerating bone during cortical defect healing

Laurent Monfoulet, Luc Malaval, Jane E. Aubin, Susan R. Rittling, Alain P. Gadeau, Jean-Christophe Fricain, Olivier Chassande

Journal:

Year:

2010

Language:

english

File:

PDF, 718 KB

english, 2010

36

Osteopontin is dispensable for protection against high load systemic fungal infection

Ikuko Sato, Nobuchika Yamamoto, Susan R. Rittling, David T. Denhardt, Motohiro Hino, Junko Morimoro, Fumihiko Sakai, Akihiko Fujie, Toshimitsu Uede

Journal:

International Immunopharmacology

Year:

2008

Language:

english

File:

PDF, 669 KB

english, 2008

37

Osteopontin expression in normal and fibrotic liver. Altered liver healing in osteopontin-deficient mice

Dionne Lorena, Ian A. Darby, Alain-Pierre Gadeau, Laetitia Lam Shang Leen, Susan Rittling, Luís C. Porto, Jean Rosenbaum, Alexis Desmoulière

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 521 KB

english, 2006

38

The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation

Noriaki Mori, Tokifumi Majima, Norimasa Iwasaki, Shigeyuki Kon, Kiyoshi Miyakawa, Chiemi Kimura, Kunio Tanaka, David T. Denhardt, Susan Rittling, Akio Minami, Toshimitsu Uede

Journal:

Year:

2007

Language:

english

File:

PDF, 1.90 MB

english, 2007

39

Osteopontin deficiency enhances parathyroid hormone/ parathyroid hormone related peptide receptor (PPR) signaling-induced alteration in tooth formation and odontoblastic morphology

Maki Morishita, Noriaki Ono, Kentano Miyai, Tomomi Nakagawa, Ryo Hanyu, Masashi Nagao, Paksinee Kamolratanakul, Takuya Notomi, Susan R. Rittling, David T. Denhardt, Henry M. Kronenberg, Yoichi Ezura,

Journal:

Tissue and Cell

Year:

2011

Language:

english

File:

PDF, 1.10 MB

english, 2011

40

Override of the Osteoclast Defect in Osteopontin-Deficient Mice by Metastatic Tumor Growth in the Bone

Tajneen Natasha, Misty Kuhn, Owen Kelly, Susan R. Rittling

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 949 KB

english, 2006

41

Osteopontin regulates interleukin-17 production in hepatitis

Hongyan Diao, Xiangdong Liu, Zhongwen Wu, Lei Kang, Guangying Cui, Junko Morimoto, David T. Denhardt, Susan Rittling, Yoichiro Iwakura, Toshimitsu Uede, Lanjuan Li

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

42

Osteopontin Deficiency Induces Parathyroid Hormone Enhancement of Cortical Bone Formation

Kitahara, Keiichiro, Ishijima, Muneaki, Rittling, Susan R., Tsuji, Kunikazu, Kurosawa, Hisashi, Nifuji, Akira, Denhardt, David T., Noda, Masaki

Journal:

Year:

2003

Language:

english

File:

PDF, 698 KB

english, 2003

43

Effects of the selective adenosine A2A receptor antagonist, SCH 412348, on the parkinsonian phenotype of MitoPark mice

Smith, Karen M., Browne, Susan E., Jayaraman, Srinivasan, Bleickardt, Carina J., Hodge, Lisa M., Lis, Edward, Yao, Leon, Rittle, Sunday L., Innocent, Nathalie, Mullins, Deborra E., Boykow, George, Rey

Journal:

European Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 499 KB

english, 2014

44

Expression of Cell Cycle-Dependent Genes in Young and Senescent WI-38 Fibroblasts

Susan R. Rittling, Katherine M. Brooks, Vincent J. Cristofalo and Renato Baserga

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 967 KB

english, 1986

45

Osteopontin-Deficient Mice are Resistant to Ovariectomy-Induced Bone Resorption

Hiroyuki Yoshitake, Susan R. Rittling, David T. Denhardt and Masaki Noda

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.13 MB

english, 1999

46

Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells

Ezura, Yoichi, Nagata, Junji, Nagao, Masashi, Hemmi, Hiroaki, Hayata, Tadayoshi, Rittling, Susan, Denhardt, David T., Noda, Masaki

Journal:

Journal of Bone and Mineral Metabolism

Year:

2015

Language:

english

File:

PDF, 589 KB

english, 2015

47

Effect of Osteopontin on Diarrhea Duration and Innate Immunity in Suckling Mice Infected with a Murine Rotavirus

Maeno, Yoshimasa, Shinzato, Masanori, Nagashima, Shigeo, Rittling, Susan R., Denhardt, David T., Uede, Toshimitsu, Taniguchi, Koki

Journal:

Viral Immunology

Year:

2009

Language:

english

File:

PDF, 7.71 MB

english, 2009

48

Corneal Wound Healing in an Osteopontin-Deficient Mouse

Miyazaki, Ken-ichi, Okada, Yuka, Yamanaka, Osamu, Kitano, Ai, Ikeda, Kazuo, Kon, Shigeyuki, Uede, Toshimitsu, Rittling, Susan R., Denhardt, David T., Kao, Winston Whei-Yang, Saika, Shizuya

Journal:

Investigative Ophthalmology & Visual Science

Year:

2008

Language:

english

File:

PDF, 920 KB

english, 2008

49

Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin

Hui, Tommy, Sørensen, Esben S., Rittling, Susan R.

Journal:

Year:

2015

Language:

english

File:

PDF, 864 KB

english, 2015

50

Osteopontin in macrophage function

Rittling, Susan R.

Journal:

Expert Reviews in Molecular Medicine

Year:

2011

Language:

english

File:

PDF, 360 KB

english, 2011